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Pharmacology All India exam 4202a3b2

Antiparkinsonian drug activating D2 receptors directly

A
Pramipixole
B
Entacapone
C
Benserazide
D
Selegiline
High-Yield Explanation
Direct D2 activators are bromcriptine , pergolide,pramipexole,ropinirole. ENtcapone and tolcapone are COMT inhibitors and selegiline is a MAO inbibitor used in PD.In PD there is decrease of dopamine in the substansia nigra. Ref:KDT 6/e p419

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