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Pharmacology Chemotherapy 41f2965c

Radiation protector drug in clinical use among the following is

A
Amifostine
B
Cisplatin
C
Mesna
D
Tirapazamine
High-Yield Explanation
Amifostine is used therapeutically to reduce the incidence of neutropenia-related fever and infection induced by DNA-binding chemotherapeutic agents including alkylating agents and platinum-containing agents . It is also used to decrease the cumulative nephrotoxicity associated with platinum-containing agents. Amifostine is also indicated to reduce the incidence of xerostomia in patients undergoing radiotherapy for head and neck cancerReference: Perez and Brady&;s textbook of radiation oncology; 6th edition

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