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Medicine General 4140f1c2

The paraneoplastic hypercalcemia in lymphoma is due to ectopic production of which of the following?

A
Parathyroid hormone-related protein
B
1,25 dihydroxyvitamin D
C
Parathyroid hormone
D
Prostaglandin E2
High-Yield Explanation
This is an impoant topic as it is frequently asked in entrance exams. Please go through it in detail: Paraneoplastic manifestation Ectopic Hormone Typical Tumor Types Hypercalcemia Parathyroid hormone-related protein Squamous cell carcinoma (head and neck, lung, skin), breast, genitourinary, gastrointestinal tumors Hypercalcemia 1,25 dihydroxyvitamin D Lymphomas Hypercalcemia Parathyroid hormone Lung, ovary Hypercalcemia Prostaglandin E2 Renal, lung Ref: Harrisons Principles of Internal Medicine, 18th Edition: Table 100-1 Paraneoplastic Syndromes Caused by Ectopic Hormone Production.

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