True about Wilson's disease
High-Yield Explanation
Wilson disease is an inborn error of metabolism due to toxic accumulation of copper in the liver, brain, cornea and other tissues.
Serum ceruloplasmin is decreased(<20 mg/dl) and the 24-hour urinary copper excretion is more than 100 micrograms/day.
Hepatic copper values usually above 250 micrograms /gram of dry weight of liver.