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Pharmacology General 4127528f

What is the dose of adrenaline in anaphylactic shock?

A
0.5 ml in 1:1000
B
0.5 ml in 1:10000
C
1 ml in 1:1000
D
1.5 ml in 1:1000
High-Yield Explanation
Ans. A. 0.5 ml in 1:1000Severe hypersensitivity reactions, anaphylactic shockIM Injection:* Adults: The usual dose is 500 micrograms (0.5ml of adrenaline 1/1000). If necessary, this dose may be repeated several times at 5-minute intervals according to blood pressure, pulse and respiratory function.* Half doses of adrenaline may be safer for patients who are taking amitriptyline, imipramine or a beta blocker.Paediatric population:* The following doses of adrenaline 1/1,000 are recommended:AgeDoseOver 12 years0.5 mg IM (0.5ml 1:1000 solution)6 - 12 years0.3 mg IM (0.3ml 1:1000 solution)6 months - 6 years0.15 mg IM (0.15ml 1:1000 solution)Under 6 months0.01mg/kg IM (0.01ml/kg 1:1000 solution)* If necessary, these doses may be repeated at 5-15 -minute intervals according to blood pressure, pulse and respiratory function.

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