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Pathology Blood 40a75717

Howell jolly bodies are seen in?

A
Iron deficiency anemia
B
Hemolytic anemia
C
Polycythemia vera
D
Multiple myeloma
High-Yield Explanation
Ans. is 'b' i.e. Hemolytic anemia Howell-Jolly bodies (HJ bodies)* These are round solid staining, dark-blue to purple inclusions. They are nuclear remanants predominatly composed of DNA.* The presence of Howel-Jolly bodies is associated with hemolytic anemia, megaloblastic anemia, hereditary spherocytosis, myelodysplastic syndrome, post splenectomy and after physiological atrophy of spleen.* Although HJ bodies are seen in all these conditions, they are most common after splenectomy.

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