Iron entry into enterocytes occurs which of the following?
High-Yield Explanation
GI Luminal non-heme iron is mostly in the Fe3+ (ferric) state and must first be reduced to Fe2+ ferrous) iron by ferrireductases, such as b cytochromes and STEAP3. Fe2+ iron is then transpoed across the apical membrane of enterocytes by divalent metal transpoer-1 (DMT1).