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Physiology Endocrinology and Reproduction 40908717

Effects of growth hormone are all except

A
Lipolysis
B
Increased protein synthesis
C
Glycolysis
D
Glycogenolysis
High-Yield Explanation
Ans. c (Glycolysis). (Ref: Ganong, Physiology, 21st ed., 402, 406)GROWTH HORMONE# It is a protein anabolic hormone containing single chain of 191 aminoacids, secreted by somatotropes# It produces positive nitrogen & phosphorous balance# It decreases body fat & Cholesterol# It increases GI absorption of Ca++.# It moblilizes FFA from adipose tissue (favours ketogenesis)# It decreases glucose uptake into some tissues- Stimulates body growth;- Stimulates secretion of IGF-1;- Stimulates lipolysis;- Inhibits actions of insulin on carbohydrate and lipid metabolism.FACTORS THAT affect SECRETION OF GROWTH HORMONEStimulate Growth Hormone SecretionInhibit Growth Hormone Secretion- Decreased blood glucose- Decreased blood free fatty acids- Starvation or fasting, protein deficiency- Trauma, stress, excitement, Exercise- Testosterone, estrogen- Deep sleep ( stages II and IV)- Growth hormone-releasing hormone- Increased blood glucose- Increased blood free fatty acids- Aging- Obesity- Growth hormone inhibitory hormone (somatostatin)- Growth hormone (exogenous)- Somatomedins (insulin-like growth factors)

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