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Pediatrics Primary Immunodeficiency 402025da

In genetic deficiency of MPO, the increased susceptibility to infection is due to:

A
Defective production of Prostaglandins
B
Defective rolling of' neutrophils
C
Inability to produce hydroxyl halide radicals
D
Inability to produce hydrogen peroxide
High-Yield Explanation
In MPO deficiency there is decreased microbial killing because of defective MPO--H2O2 system, so there is an inability to produce hydroxyl halide radicals.

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