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Microbiology General 400e4d0a

Reversion of Neisseriagonorrhoeae from a fimbriated (fim 1) to a non-fimbriated (fim 2) state would result in which one of the following phenomena?

A
Inability of N. gonorrhoeae to colonize the mucosal epithelium
B
Reversion to a Gram-positive stain
C
Death of the organism
D
Loss of serologic specificity
High-Yield Explanation
Bacteria may shift rapidly between the fimbriated (fim +) and the non-fimbriated (fim -) states. Fimbriae function as adhesions to specific surfaces and consequently play a major role in pathogenesis. Lack of fimbriae prevents colonization of the mucosal surface by the bacterium.

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