A pregnant mother is treated with oral anticoagulant. The likely congenital malformation that may result in the fetus is:
High-Yield Explanation
Ans. is d, i.e. Chondrodysplasia punctateRef. Dutta Obs. 7/e, p 511Warfarin is an anticoagulant drug.Action: Interferes with the synthesis of the vitamin K dependent factors like II, VII, IX and X.Side effects:HemorrhageIt leads to:-Contradi's syndrome: skeletal and facial anomalies in the fetus-Chondrodysplasia punctata in the fetus.Miscarriage, IUGR and stillbirths accentuates neonatal hypothrombinemia.