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Pharmacology NSAIDs, Gout and Rheumatoid Ahritis 3fcd72e6

Which of the following drugs reduces the activity of phospholipase A2?

A
Alprostadil
B
Aspirin
C
Ibuprofen
D
Prednisolone
High-Yield Explanation
Prednisolone: It is a powerful anti-inflammatory agent. It acts by inhibiting the synthesis of PG, TX and LT the inhibition of phospholipase A2 enzyme. It is most impoant mechanism of anti-inflammatory action is the inhibition of chemotaxis.

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