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ENT General 3f5ba2cf

All statement about Plummer–Vinson syndrome are true except -

A
Commonly leads to carcinoma in lower third of esophagus
B
Common with iron deficiency
C
Common in females
D
Premalignant
High-Yield Explanation
Plummer-Vinson syndrome Plummer-Vinson syndrome, also known as Brown-Kelly-Paterson syndrome or sideropenic dysphagia, seen in middle-aged edentulous women. The plummer Vision Paterson Brown-Kelly Syndrome is characterized by : - Dysphagia Chronic iron deficiency anaemia Atrophic oral mucosa and glossitis Brittle, spoon-shaped fingernails (Koilonychia) The cause of dysphagia is usually a cervical esophageal web, but abnormal pharyngeal and esophageal motility may play a role. The syndrome characteristically occurs in middle-aged edentulous (without teeth) women. It is a premalignant lesion. Approximately 10% of patient develop squamous cell Ca of esophagus, oral cavity or the hypopharynx. As iron-deficiency anemia is a common finding, it is also known as sideropenic dysphagia. Carcinoma develops in the postcricoid region (not in the lower third oesophagus).

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