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Pathology General 3f2fa7fb

Li-Fraumeni syndrome has the risk of development of:

A
Squamous cell carcinoma
B
Basal cell carcinoma
C
Osteosarcoma
D
Both 1 & 3
High-Yield Explanation
Li-Fraumeni syndrome (germline TP53 mutation) is a predisposing factor for osteosarcoma development. Reference: Shafer’s Textbook of ORAL PATHOLOGY Eighth Edition page no 227

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