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Pharmacology General 3ea5eac2

Hand, foot mouth syndrome is caused by ?

A
Cisplatin
B
Methotrexate
C
5 FU
D
Metycergide
High-Yield Explanation
Ans. is 'c' i.e., 5FU Hand foot syndrome Hand foot syndrome is a form erythromyelalgia manifested as tingling, numbness, pain, erythma, swelling and increased pigmentation of hands and feet. Two most common drugs causing 'Hand foot' syndrome are: Capecitabine (most common) 5-FU (2nd most common) Drugs causing 'Hand foot' syndrome Commonly associated drugs Capecitabine Surafenib Cytarabin 5-FU Doxorubicin (liposomol) Rarely associated drugs Cisplatin Etoposide 6-MP Cyclophosphamide Hydroxyurea Suramin Docetaxel Methotrexate Paclitaxel Daunorubicin Mitotane

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