A 35-years old lady presented with dysphagia, nocturnal asthma and weight loss for 6 years. The most probable diagnosis is

Heaburn and regurgitation are the typical symptoms of GERD. Extraesophageal syndromes with an established association with GERD include a chronic cough, laryngitis, asthma, and dental erosions. A multitude of other conditions including pharyngitis, chronic bronchitis, pulmonary fibrosis, chronic sinusitis, cardiac arrhythmias, sleep apnea, and recurrent aspiration pneumonia have proposed associations with GERD.However, in both cases, it is impoant to emphasize the word association as opposed to causation.Ref: Harrison; 19th edition; Page no: 1907