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Pathology Haematology 3e4d72bb

Multiple myeloma is diagnosis by-

A
24 hour urine protein
B
Kidney biopsy
C
>10% plasmacytoma
D
Rouleaux formation in blood
High-Yield Explanation
Answer is option4, roulex formation in blood. Multiple myeloma Much rouleaux formation of the red cells is in this thick area of red cell distribution. This is pathologic rouleaux in contrast to normal stacking of red cells in a thick area of a normal blood smear. The background has a bluish tinge. Two small lymphocytes and one mature neutrophil are in the field. Multiple myeloma (Blood - 50X) The stacking of cells (rouleaux formation) facilitates the rate of red cell sedimentation, a phenomenon that may be seen on a peripheral smear. www.labsnet.medical

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