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Pharmacology Cardiovascular system 3e3f49f5

Which of the following statement about diazoxide is false

A
It acts by causing prolonged opening of ATP dependent potassium channels in beta cells
B
It can cause severe hypoglycemia
C
It can be used to treat patients with insulinaemia
D
It is used as an antihypeensive agent
High-Yield Explanation
Diazoxide cause hyperglycemia and not hypoglycemia Diazoxide is a potassium channel activator, which causes local relaxation in smooth muscle by increasing membrane permeability to potassium ions. This switches off voltage-gated calcium ion channels, preventing calcium flux across the sarcolemma and activation of the contractile apparatus Refer katzung 11e p180

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