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Unknown General 3e037a56

BCR ABL gene mutation is seen in ?

A
CML
B
AML
C
CLL
D
ALL
High-Yield Explanation
ANSWER: (A) CMLREF: Robbins 7th ed p. 697BCR gene on chromosome 9 gets translocated to ABL gene on chromosome 22 leading to the formation of a fusion protein with a tyrosine kinase activity.

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