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Medicine Oesophagus 3ddbecce

Barrett's esophagus causes which cancer:

A
Adenocarcinoma
B
Squamous cell CA
C
Carcinoid tumor
D
Esophageal leiomyoma
High-Yield Explanation
Ans. (a) AdenocarcinomaRef: Harrison's 17th ed. Ch. 286* Metaplastic columnar epithelium develops during healing of erosive esophagitis with continued acid reflux since columnar epithelium is more resistant to acid- pepsin damage than is squamous epithelium.* The metaplastic epithelium has different epithelial types, including goblet cells and columnar cells.* Finding intestinal metaplasia with goblet cells in the esophagus is diagnostic of Barrett's esophagus; this type of mucosa is thought to be at risk of cancer

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