Physiology All India exam 3d733b33

True about leukemia in Down's syndrome is

Acute leukemia less common than gen population

AML more common than ALL

Prog in AML is better than gen population

If diagnosed with ALL, should be given higher doses of methotrexate

High-Yield Explanation

In this group of patients, the repoed event-free survival rates have ranged from 80 to 100%. On the other hand, the outcome of Down syndrome children with acute lymphoblasticleukemia (ALL) has been historically considered worse than the outcome of ALL patients withoutDown syndrom Ref ganong's review of medical physiology 25e

True about leukemia in Down's syndrome is

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