Full 2L QBank
Pathology Respiratory system 3d6f116c

The most common paraneoplastic syndrome associated with lung cancer?

A
SIADH
B
Cushings syndrome
C
Hypercalcemia
D
Polycythemia
High-Yield Explanation
*Most common paraneoplastic syndrome: Hypercalcemia *Most common endocrinopathy in paraneoplastic syndrome: Cushing syndrome*Most common carcinoma associated with Cushing syndrome: Lung carcinoma*The cancer patients develop Cushing syndrome due to excess production of pro-opiomelanocoin and coicotrophin.*Most common paraneoplastic syndrome in squamous cell lung carcinoma: Hypercalcemia*Most common paraneoplastic syndrome in small cell lung carcinoma: SIADH*Since among all lung cancers, squamous cell carcinoma is common than small cell carcinoma, Most common paraneoplastic syndrome in lung cancer is HypercalcemiaRef: Robbins 8/e p321

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