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Medicine General 3d266c0a

Which of the following drugs is used for treatment of myoclonus?

A
Valproate
B
Levetiracetam
C
Primidone
D
All of the above
High-Yield Explanation
Treatment primarily consists of treating the underlying condition or removing an offending agent. Pharmacologic therapy involves one or a combination of GABAergic agents such as valproic acid (1200-3000 mg/d), piracetam (8-20 g/d), clonazepam (2-15 mg/d), or primidone (500-1000 mg/d). Recent studies suggest that levetiracetam may be paicularly effective. Ref: Harrison's principle of internal medicine 17th edition, chapter 367.

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