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Pediatrics Miscellaneous 3d21cc5f

All of the following are true about Reyes' syndrome, EXCEPT

A
Follows viral infection
B
|PG
C
Should be treated as for hepatic failure
D
Good prognosis
High-Yield Explanation
(D) Good prognosis # REYE SYNDROME is characterized by acute noninflammatory encephalopathy and hepatic failure.> Although the etiology of Reye syndrome is unknown, the condition typically occurs after a viral illness, particularly an upper respiratory tract infection (URTI), influenza, varicella, or gastroenteritis, and it is associated with the use of aspirin during the illness. The discoveries of inborn errors of metabolism that have manifestations similar to those of Reye syndrome and a dramatic decrease in the use of aspirin among children have made the diagnosis and occurrence of Reye syndrome rare.> Some have postulated that salicylates stimulate the expression of inducible nitric oxide synthase (iNOS) because of findings of iNOS stimulation in African children with fatal malaria. Malaria causes symptoms similar to those of Reye syndrome and is often treated with aspirin.

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