Which anticancer drug causes hypercoagulable syndrome?

Hypersensitivity reaction manifested by fever, chills, nausea, and vomiting, uicaria, bronchospasm, respiratory failure and hypotension; i ed risk of both clotting and bleeding as a result of alterations in various clotting factors; pancreatitis, and neurological toxicity. Ref: KD Tripathi 8th ed.