Resolution of inflammation caused by:

TNF Alfa, IL 10 and IL 1 receptor antagonist REF: See APPENDIX-19 for list of "Cytokines" The anti-inflammatory cytokines are a series of immune-regulatory molecules that control the pro-inflammatory cytokine response. Cytokines act in conce with specific cytokine inhibitors and soluble cytokine receptors to regulate the human immune response. Their physiologic role in inflammation and pathologic role in systemic inflammatory states are increasingly recognized. Major anti-inflammatory cytokines include interleukin (IL)-1 receptor antagonist, IL-4, IL-6, IL-10, IL-11, and IL-13. Specific cytokine receptors for IL-1, tumor necrosis factor-alpha, and IL-18 also function as pro-inflammatory cytokine inhibitors. Resolvins and protectins are new families consisting of distinct chemical series of lipid-derived mediators, each with unique structures and apparent complementary anti-inflammatory actions