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Medicine Miscellaneous 3ccb3f88

Infliximab is contraindicated in

A
Crohn's disease
B
Intestinal tuberculosis
C
Ankylosing spondylitis
D
Rheumatoid arthritis
High-Yield Explanation
(B) Intestinal tuberculosis # Infliximab is a drug used to treat autoimmune disorders.> Infliximab is known as a "chimeric monoclonal antibody" (the term "chimeric" refers to the use of both mouse (murine) and human components of the drug i.e. murine binding Fab domains and human constant Fc domains).> Case studies have been done into other uses of infliximab, such as to treat skin diseases.> Infliximab has been approved for treating ankylosing spondylitis, Crohn's disease, fistulizing Crohn's disease, pediatric Crohn's disease, psoriatic arthritis, psoriasis, rheumatoid arthritis, and ulcerative colitis.> Infliximab is also prescribed (out of indication) for the treatment of Behcet's disease and infusions of infliximab have been used successfully in the treatment of sciatica due to slipped discs

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