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Pathology Plasma Cell Disorders and Multiple myeloma 3c21f444

A 70-year-old male has a pathologic fracture of femur. The lesion appears a lytic on X-rays film with a circumscribed punched out appearance. The curetting from fracture site is most likely to show which of the following?

A
Diminished and thinned trabecular bone
B
Sheets of atypical plasma cells
C
Metastatic prostatic adenocarcinoma
D
Malignant cells forming osteoid bone
High-Yield Explanation
Old patient along with lytic circumscribed punched out X-ray appearance suggests multiple myeloma Multiple myeloma most often presents as multifocal destructive bone tumors composed of plasma cells throughout the skeletal system. It shows sheets of atypical plasma cells.

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