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Biochemistry DNB 2018 3c0df9c2

Telomerase has action of:

A
DNA polymerase 1
B
DNA polymerase 2
C
DNA polymerase 3
D
Reverse transcriptase
High-Yield Explanation
Telomerase - Telomerase is a ribonucleoprotein paicle required for telomere maintenance. Telomerase contains an RNA that serves as the template, not the primer , for the synthesis of telomeric DNA by the reverse transcriptase of telomerase. Telomeric RNA has no catalytic activity. As a reverse transcriptase, telomerase synthesizes DNA using its RNA template and so is an RNA-transcriptase DNA polymerase. Telomerase is highly active in the early embryo, and after bih it is active in the reproductive and stem cell. Telomerase activity high in cancer cell.

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