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Skin General 3c08e263

True about drug induced SLE is:

A
CNS manifestation are common
B
Renal involvement is common
C
Antihistone antibodies are found in many
D
All with antibodies progress to lupus
High-Yield Explanation
C i.e. Antihistone antibodies are found Drug induced lupus is caused by procainamide, hydralazine, isoniazid (but not chloroquine) Q. It is a syndrome of positive ANA associated commonly with antihistone antibodies, fever, malaise, ahritis or intense ahralgiaVmyalgias, serositis, and/or rashQ. It occurs predominantly in whites, has less female predilection than SLE, rarely involves brain or kidneys, is rarely a/w anti ds DNA and usually resolves over several weeks after discontinuation of offending drugQ.

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