A patient has a frequent tendency of migraine attacks. Which of the following drug should be given as prophylaxis?

Prophylaxis of migraine is required if the attacks are frequent (>2-3 per month). The drugs useful for prophylaxis are:  Propranolol is the most commonly used drug for prophylaxis of migraine attacks. Timolol, atenolol, metoprolol and nadolol can also be used but the drugs with ISA (e.g. pindolol) are ineffective.