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Microbiology General 3bcd6b57

Select the false statement about P. jiroveci?

A
It is seen in only immunocompromised individuals
B
Frequently associated with CMV
C
May be associated with pneumatocele
D
Diagnosed with sputum microscopy
High-Yield Explanation
Ans. is 'b' i.e., Frequently associated with CMV Lets see each option one by one. Robbin's Option 'a' - See following statements of Topley's mycology; "Pneumocystis are found in low number in the lungs of mammalian hosts with intact immune system and in more abundance in homeotherms with compromised immune status". "A decrease in cell mediated immunity is the single most impoant risk factor for the development of pneumocystis pneumonia". So, P. jiroveci may be seen both in immunocompromised individuals and individuals with intact immune system, but it causes pneumonia only in immunocompromised individuals. Option 'b' - P.jirovecii may be associated with CMV infection but it is not usually associated with CMV infection. Option 'c' - P.jirovecii may be associated with penumatocele formation but pneumatoceles are not associated in all cases of P.jirovecii pneumonia. Option 'd' - Option 'c' is paially correct. - Usually the diagnosis of pneumocystis pneumonia is confirmed by histopathologic staining of BAL fluid collected by bronchoscopy, but it can also be diagnosed by microscopic examination of induced sputum. Diagnosis

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