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Anatomy Other topics and Adverse effects 3bcd156e

Which of following statements about extrapyramidal effects of antipsychotic drugs is FALSE?

A
Caused by blockade of dopamine receptors
B
Less likely to be produced by clozapine than by chlorpromazine
C
Can be countered to some degree by antimuscarinic drugs
D
Haloperidol does not cause extrapyramidal syndrome
High-Yield Explanation
(Ref: KDT 6/e p430, 431, 432) Extrapyramidal adverse effects of antipsychotic drugs are due to blockade of dopamine receptors. These are less often seen with atypical anti-psychotics like clozapine and risperidone (and more often with classical drugs like haloperidol and chlorpromazine). These effects can be treated with central anticholinergic drugs like benztropine and trihexiphenidyl.

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