MC cause of death in an adult with PDA is –

A most common cause of death in PDA is CCF. A second most common cause of death is infective endocarditis. Course and complications of PDA Spontaneous closure of PDA does not usually occur in full-term infants because PDA in term infants results from a structural abnormality of ductal smooth muscles (In premature infants spontaneous closure may occur because PDA in these infants results from unresponsiveness to oxygen). Pulmonary vascular pressure regress slower than normal and maximum decrease occurs around 6-8 weeks (normally at 1-3 weeks). Common complications are : - CHF → MC complication and MC cause of death        Infective endocarditis Pulmonary hypertension  Pneumonia Aneurysm of PDA → Rare and possible rupture in adult life