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Pathology General 3b76d608

True about fresh frozen plasma -a) Used for treatment of antithrombin-3 deficiencyb) Used for treatment of Vit-K deficiencyc) Used for replacing factor VIII & IX, if deficiencyd) Best alternative for platelet

A
ac
B
a
C
ad
D
ab
High-Yield Explanation
Fresh frozen plasma (FFP)  FFP is defined as the fluid portion of human blood that has been centrifuged, separated, and frozen solid at -18°c within 6 hours. FFP contains stable coagulation factors and plasma proteins : - i. Fibrinogen ii. Antithrombin   iii. Albumin & Immunoglobulin       iv. Protein C,S  v. Factor II, V, VII, ix, X, XI  Uses There are few specific indications for the the use of FFP. These indications are generally limited to the treatment of deficiency of coagulation proteins for which specific factor concentrates are unavailable or undesirable. Indications for the use of FFP are : - Deficiencies of factor II, V, VII, IX, X and XI when specific component therapy is neither available nor appropriate. Emergency reversal of warfarin effect. In vit K deficiency as replacement for Vit K dependent factors (II, VII, IX, X) Antithrombin III deficiency After massive blood transfusion. In immunodeficiency as a source of immunoglobulin TTP Note : Options 'c' is partially correct, PPP can be used for deficiency of factor IX but not for factor VIII.

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