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Pathology General 3b55c7f4

Massive splenomegaly with pancytopenia -

A
CLL
B
Pure red cell aplasia
C
CML
D
Myelofibrosis
High-Yield Explanation
Ans. is 'd' i.e., Myelofibrosiso Massive splenomegaly is referred to as extension of spleen greater than 8 cm below the left costal margin or weight of spleen more than 1 Kg.o Causes of massive Splenomegaly are - CML Polycythemia vera Autoimmune hemolytic anemia Lymphomas Gaucher's disease Diffuse splenic hemangiomatosis Hairy cell leukemia CLL Myelofibrosis Sarcoidosiso Amongst these conditions pancytopenia is seen in i.e., massive splenomegaly with pancytopenia : - o Hairy cell leukemia Myelofibrosis Gaucher's disease

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