Pharmacology General 3b339776 Which of the following antiglaucoma drug can lead to drowsiness A Apraclonidine B Dipevefrine C Timolol D Brimonidine High-Yield Explanation Brimonidine is α2 - blocker used for glaucoma that depress CNS and can lead to drowsiness. It can cross BBB and also lead to apnea in newborns.