Major neurotransmitter released at end organ effectors of the sympathetic division of the autonomic nervous system
High-Yield Explanation
In the parasympathetic division, neurons are cholinergic (that is, acetylcholine is the primary neurotransmitter). In sympathetic division, neurons are mostly adrenergic (that is, epinephrine and norepinephrine function as the primary neurotransmitters). Ref guyton and hall textbook of medical physiology 12/e pg 83