True about myxoma is -

Cardiac myxomas o Most common primary tumor of the adult heart. o Benign neoplasms thought to arise from primitive multipotentmesenchymal cells. o Familial syndromes associated with myxomas have activating mutations in the GNAS1 gene, encoding a subunit of G protein (Gsa) (in association with McCune-Albright syndrome) or null mutations in PRKARIA, encoding a regulatory subunit of a cyclic-AMP- dependent protein kinase (Carney complex). o About 90% of myxomas arise in the atria, with a left-to-right ratio of approximately 4:1.