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Physiology Endocrinology 3a569115

Half-life of insulin receptor is

A
3 hr
B
7 hr
C
12 hr
D
24 hr
High-Yield Explanation
The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of tyrosine kinase receptors. Metabolically, the insulin receptor plays a key role in the regulation of glucose homeostasis, a functional process that under degenerate conditions may result in a range of clinical manifestations including diabetes and cancer. The half-life of insulin receptor is about 7 hrs.Ref: Ganong&;s review of medical physiology;24th edition; page no-437

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