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Microbiology General 3a238922

All of the following statements about hybridoma technology are true except -

A

Specific antibody producing cells are integrated with myeloma cells

B

Myeloma cells with mutation salvage pathway grows well in HAT medium.

C

Aminopterin, a folate antagonist, inhibits denovo pathway

D

HGPRT ase and thymidylate synthetase are required for salvage pathway

High-Yield Explanation

Myeloma cells lacks HGPRT enzyme, hence they cannot grow well in HAT medium.' Ref: Apurba Sastry’s Essentials of Medical Microbiology p117

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