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Pharmacology General 3a11389e

A 50–year old man has a history of frequent episodes of renal colic with high calcium renal stones. The most useful diuretic in the treatment of recurrent calcium stones is :

A
Furosemide
B
Spironolactone
C
Hydrochlorothiazide
D
Acetazolamide
High-Yield Explanation
Thiazides cause hypercalcemia by decreasing the renal excretion of Ca2+. These are useful in a patient having hypercalciuria. In such a patient, thiazides decrease the excretion of Ca2+ in the kidney and thus reduces the chances of stone formation.

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