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Medicine Fluid and electrolytes 39eef9f6

Hypercalcemia caused by which one of the following is most likely to respond to treatment with coicosteroids?

A
Primary hyperparathyroidism
B
Milk alkali syndrome
C
Sarcoidosis
D
Paget's disease
High-Yield Explanation
Hypercalcemia is a highly prevalent complication of sarcoidosis. Hypercalcemia in sarcoidosis is due to the uncontrolled synthesis of 1,25-dihydroxyvitamin D3 by macrophages. 1,25-dihydroxyvitamin D3 leads to an increased absorption of calcium in the intestine and to an increased resorption of calcium in the bone Ref Davidson 23rd edition pg 364

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