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Physiology General 392b24c4

Paterson-Kelly syndrome is associated with the following deficiency:

A
Iron
B
Zinc
C
Magnesium
D
Molybdenum
High-Yield Explanation
In long-standing iron deficiency, mucosal atrophy of laryngopharynx may lead to web formation in the postcricoid region, thereby giving rise to dysphagia (Paterson-Kelly also known as Plummer-Vinson syndrome). It is also associated with koilonychia, angular stomatitis, and a sore tongue. If these alterations are of long duration, they may lead to pharyngeal carcinoma. Ref: Beutler E. (2010). Chapter 42. Disorders of Iron Metabolism. In J.T. Prchal, K. Kaushansky, M.A. Lichtman, T.J. Kipps, U. Seligsohn (Eds), Williams Hematology, 8e.

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