Microbiology
Immunology Pa 1 (Immune Response, Antigen-Antibody Reactions, Hypersensitivity, Structure of Immune System, Immunodeficiency Disorders)
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Which is concerned with cell mediated immunity
High-Yield Explanation
Option 1, 2, 3, 4 Cell-mediated immunity: It is mediated by both activated T helper cells and cytotoxic t cells. Cytokines secreted by Th cells activate various phagocytic cells, enabling them to phagocytose and kill microorganisms. This type of cell-mediated immune response is especially impoant against a host of bacterial and protozoal pathogens. CTLs play an impoant role in killing virus-infected cells and tumor cells. Major Functions of Cell-Mediated Immunity (T Cells) 1. Host defense against infection (especially M. tuberculosis, fungi, and virus-infected cells). 3. Graft and tumor rejection 4. Regulation of antibody response (help and suppression) Humoral immunity: B lymphocytes produces antibodies and conve into plasma cell which are responsible of immunogenic memory