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Pathology Disorders of Gallbladder and Extrahepatic Biliary Tract 38ab88c6

All of the follow ing are risk factors for carcinoma gall bladder, except -

A
Typhoid carriers
B
Adenomatous gall bladder polyps
C
Choledochal cysts
D
Oral contraceptives
High-Yield Explanation
Ans. is 'd' i.e., Oral contraceptives No risk of Ca G.B. has been noted with the use of oral contraceptiveso Risk factors for Ca Gall bladder are :i) Gall stonesApproximately 90% of patients with Ca GB have gall stonesSize of the stone has a direct relationship with development of carcinoma, the risk is ten times more for larger stones (3 cm in diameter) than for stones less than 1 cm in diameterThe risk is higher with symptomatic than asymptomatic stones.ii) Adenomatous gall bladder polyps (particularly polyps larger than 10 mm)Calcified (porcelain) gall bladderCholeduochal cystEstrogensAnomalous pancreaticobiliary duct junctionExposure to carcinogens (azotoulene, nitrosamine)Typhoid carriersSclerosing cholangitisCholecystoenteric fistula Ulcerative colitis o ASI Surgery mentions two other risk factorsChemicals used in rubber industryUse of adulerated mustard cooking oil in India

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