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Pharmacology Anaesthesia 38610a25

TRUE statements regarding halothane is

A
Hepatitis occurs in susceptible individuals after repeated dose
B
It potentiates competitive neuromuscular blockers
C
Causes respiratory depression
D
All of the above
High-Yield Explanation
(All of the above) (339-40-KDT) (372-KDT 6th)HALQTHANE - volatile liquid with sweet odour, non irritant and non inflammable, pleasant and rapid action.* * It is not a good analgesic or muscle relaxant, it potentials competitive neuromuscular blockers.* * Halothane causes direct depression of myocardial contractility by reducing intracellular Ca** concentration.* * Halothane causes relatively greater depression of respiratory, breathing is shallow and rapid* ** Pharyngeal and laryngeal reflexes are abolished early and coughing is suppressed, while bronchi dilates - "preferred for asthmatics"* * Hepatitis occurs in susceptible individuals specially after repeated use* * Malignant hyperthermia occurs rarely

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