Urinary metabolite of progesterone
High-Yield Explanation
Pregnanediol is most abundant plasma as well as urinary metabolite of progesterone. In plasma 80 % is bound to albumin and 18 % to coicosteroid binding globulin. Progesterone has sho half-life and in liver it is conveed to Pregnanediol and conjugated to glucoronic acid and excreted in urine. Ref: Ganong review of Medical physiology 22nd edition Pgno: 443