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Pharmacology Anti-Parasitic Drugs 38204e22

What is DOC for treatment of Trichomonal vaginalis ?

A
Mebendazole
B
Tinidazole
C
Albendazole
D
Metronidazole
High-Yield Explanation
1. Drug of choice for Trichomoniasis is Metronidazole. 2. Treatment for Trichomoniasis : Metronidazole 400mg TDS for 7 days or 2g single dose, (or) Tinidazole 600mg daily for 7 days or 2g single dose, (or) Secnidazole 2g single dose. 3. Treatment failures owing to the presence of Metronidazole-resistant strains of T. vaginalis are becoming increasingly common. Most of these cases can be treated successfully by giving a second 2g dose to both patient and sexual paner. In addition to oral therapy, the use of a 500-1000mg vaginal suppository may be beneficial in refractory cases.

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