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Pathology Endocrinology 37cb530f

Among the following conditions of hypercalcemia, PTH is not elevated in

A
Parathyroid adenoma
B
Familial hypocalciuric hypercalcemia
C
Parathyroid hyperplasia
D
Sarcoidosis
High-Yield Explanation
In individuals with primary hyperparathyroidism, serum PTH levels are inappropriately elevated for the level of serum calcium, whereas PTH levels are low to undetectable in hypercalcemia caused by of non-parathyroid diseasesSarcoidosis is a non-parathyroid cause of hypercalcemiaFamilial hypocalciuric hypercalcemia, a rare autosomal dominant disorder caused by loss-of-function mutations in the parathyroid calcium-sensing receptor gene (CASR), which results in decreased sensitivity to extracellular calcium. PTH is elevated.Robbins pathology 9e pg: 1103

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